The most important aspect of Bacillus coagulans is that it generates spores and imparts several health benefits of non-spore forming probiotics along with its ability to tolerate heat and stressful requirements of food processing as well as gastrointestinal tract conditions. The efficacy of beneficial probiotics is attributed to their tolerance to stress factors while most probiotics have a relatively short and unstable shelf life. The mechanism behind establishment of gut homeostasis involves promotion of growth of other beneficial microbes and suppression of pathogen and pathogen induced inflammatory response of intestinal mucosa. The mechanisms by which spore forming probiotics could enhance health of the host include stimulation of immune system, synthesis of different antimicrobials, like bacteriocins, enzymes and modulation of the composition of gut microbiota. isolated from such indigenous foods has been studied and are being used for the commercial preparations of functional products. The palatability and health promoting characteristic of these locally produced supplements has also attracted the attention of global market. are among the popular functional foods naturally harboring the blend of Bacillus spp. For example, Natto (Japan), Gari (Africa) TapaiUbi (Malaysia), Douchi (China), Soibum (India), Ugba (Nigeria) etc. A diverse range of Bacillus species are found to be associated to the natural fermentation of soy, locust bean, maize, rice and many more substrates. by human beings is frequent through fermented foods and raw vegetables. The consumption of vegetative cells and spores of Bacillus spp. coagulans are present in various natural food sources. coagulans bacterium can be called ‘the king of probiotics’ due to its high stability in the gastrointestinal tract, non-toxic action, and pharmacological activity. The probiotic is available in capsules and sachets, as well as in functional foods and dietary supplements in a dormant, spore-like state until they get activated in the intestines. coagulans is not merely a component for dietary supplements but a number of drugs containing this bacterium have entered the global pharmaceutical market and have already proven their clinical efficacy. coagulans can germinate into vegetative bacteria showing probiotic activity and later excreted from the body without alteration of the individual human microflora’s composition.
In the spore form, it is resistant to gastric fluid and bile and cannot be lysed during manufacturing processes and storage. (6) maintain viability both in food and drugs. (3) grow fast, colonize the intestinal tract, and then leave the body (2) adhere to intestinal epithelial cells (1) survive the passage through the gastrointestinal tract, acid and bile resistant. In probiotics Bacillus coagulans, a spore-forming microorganism, is one of the most promising candidate since it meets all the criteria to be considered as probiotic in human and animal feed industry: A variety of good bacteria has been explored to improve general health and well-being of humans and animals. These helpful microbes exert beneficial effects on host health by creating microbial balance in the digestive system. Probiotics are made of good live bacteria and/or yeasts that naturally live in our body.
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